Chronic periodontitis is a prevalent and chronic inflammatory condition affecting the supporting structures of the teeth, leading to tooth loss if left untreated. Chlorhexidine, a widely used antimicrobial agent, has demonstrated efficacy in the management of periodontal diseases. This clinical study aims to compare the effectiveness of two different formulations of chlorhexidine gel in the treatment of chronic periodontitis. A total of 100 patients diagnosed with chronic periodontitis were randomly assigned to two treatment groups: Group A received chlorhexidine gel formulation X, while Group B received chlorhexidine gel formulation Y. Both groups underwent a standardized periodontal treatment protocol, including scaling and root planing, followed by the application of their respective chlorhexidine gel formulations. Periodontal parameters, such as probing pocket depth (PPD), clinical attachment level (CAL), and gingival inflammation index (GI), were measured at baseline and after three months. The results were statistically analyzed to determine the comparative efficacy of the two formulations. The findings of this study will contribute valuable insights to clinicians in selecting the most effective chlorhexidine gel formulation for the management of chronic periodontitis.

Chronic periodontitis, chlorhexidine gel, periodontal disease

Sajjan P, Laxminarayan N, Kar PP, Sajjanar M. Chlorhexidine as an Antimicrobial Agent in Dentistry – A Review. OHDM 2016;15:93-100.

Darby I. Non-surgical management of periodontal disease. Aust Dent J. 2009;54(Suppl 1):S86–95.

Addy M, Moran JM. Clinical indications for the use of chemical adjuncts to plaque control: chlorhexidine formulations. Periodontol 2000. 1997;15:52–54.

Jones CG. Chlorhexidine: is it still the gold standard? Periodontol 2000. 1997;15:55–62.

Denton GW. Chlorhexidine. In: Block SS, editor. Disinfection, sterilization and preservation. 4th ed. Philadelphia: Lea and Febiger; 1991. pp. 274–289.

Schiott CR. Effect of chlorhexidine on the microflora of the oral cavity. J Periodont Res. 1973;8(suppl):7–10.

Page RC, Eke PI. Case definitions for use in population based surveillance of periodontitis. J Periodontol. 2007;78(Suppl. 7):1387–1399.

Lange DE, Plagmann HC, Eenboom A, Promesberger A. Clinical methods for the objective evaluation of oral hygiene. Dtsch Zahnarztl Z. 1977;32(1):44–47.

Green JC, Vermillon JR. The simplifield oral hygene index. J Am Dent Assoc. 1964;68:7–13.

Lobene RR, Weatherford T, Ross NM, Lamm RA, Menaker L. A modified gingival index for use in clinical trials. Clin Prev Dent. 1986;8(1):3–6.