Mechanical jaundice is a severe symptomcomplex developing as a complication of some diseases and most frequently accompanies cholelithiasis, benign strictures of choledochiasis, primary and metastatic lesions of hepatopancreatoduodenal organs in malignant neoplasms [1,12]. Biliary outflow disorder leads to biliary hypertension and, as a result, to suppression of hepatocyte function and its death. In most cases, mechanical jaundice is accompanied by cholangitis, cholangiogenic liver abscesses, sepsis, hepatic and renal failure, which in turn leads to a number of pathogenic mechanisms leading to general intoxication, coagulation disorders, reduced immune response and multiple organ failure[14].

Mechanical jaundice, liver, cholelithiasis

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