The review is devoted to the citicoline application in the complex treatment and rehabilitation of patients with acute ischemic stroke. The results of numerous experimental and clinical studies of the effect of citicoline on ischemia and hypoxia of the brain are presented. The basic pharmacological properties of citicoline, which has a complex neuroprotective effect are highlighted. Data are presented on the latest multicenter placebo-controlled trials of the drug in acute stroke. The basic principles of successful neurorehabilitation in stroke are discussed: early onset, continuity, continuity, multidisciplinary organizational approach, combination of rehabilitation measures and medication support of neuroplasticity [4,6].

Ischaemic stroke, neuroprotection, reparative therapy

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