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Evaluating the Effectiveness of HPV Vaccination in Preventing Oral and Oropharyngeal Cancers Among Men: An Epidemiological Review
Divya Motupalli , MPHGH, Faculty of Health, Wellbeing & Social Care, Global Banking School, Oxford Brookes University, Manchester, United Kingdom Rupali Chauhan , MPH, Faculty of Health, Wellbeing & Social Care, Global Banking School, Oxford Brookes University, Manchester, United Kingdom Kennedy Oberhiri Obohwemu , PhD, Faculty of Health, Wellbeing & Social Care, Global Banking School, Oxford Brookes University, Birmingham, United Kingdom; and PENKUP Research Institute, Birmingham, United Kingdom Shubham Sharma , MDS, Independent Researcher, Manchester, United Kingdom Gabriel Olaoluwa Abayomi , PhD, Faculty of Health, Wellbeing & Social Care, Global Banking School, Oxford Brookes University, Manchester, United Kingdom Olusunmola Osinubi , PhD, Faculty of Health, Wellbeing & Social Care, Global Banking School, Oxford Brookes University, Birmingham, United Kingdom Oluwadamilola R. Tayo , MPH,Faculty of Health, Wellbeing & Social Care, Global Banking School, Oxford Brookes Univ Samuel O. Adejuyitan , MSc, Department of Project Management, School of Computing, Engineering and Physical Sciences, University of the West of Scotland, United KingdomAbstract
INTRODUCTION
Concerns and observations have been expressed regarding the multifaceted nature of Human Papilloma Virus (HPV) infections and their implications for public health, particularly considering recent epidemiological trends and evolving vaccination strategies. HPVs are small double-stranded deoxyribonucleic acid (DNA) viruses approximately 8kb in length from the family Papillomaviridae1, long recognized as significant etiological agents for several sexually transmitted diseases, including genital warts. In recent years, however, its role in the pathogenesis of various malignancies, notably cervical and oropharyngeal cancers, has become increasingly evident. The virus primarily infects epithelial cells, residing on the mucosal surfaces—such as the rectum, sexual organs, and oral cavity—as well as on the skin, thereby establishing persistent infections that can culminate in neoplastic transformation1.
Keywords
References
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Copyright (c) 2025 Divya Motupalli, Rupali Chauhan, Kennedy Oberhiri Obohwemu, Shubham Sharma, Gabriel Olaoluwa Abayomi, Olusunmola Osinubi, Oluwadamilola R. Tayo, Samuel O. Adejuyitan
This work is licensed under a Creative Commons Attribution 4.0 International License.