This article examines the factors influencing adherence to antiretroviral therapy in ARVT among HIV-infected children. HIV infection is a chronic infectious disease with a progressive course, characterized by a specific lesion of the immune system with the development of immunodeficiency, which is manifested by secondary diseases. In this connection, people living with HIV (PLHIV) need medical care for the rest of their lives.

Antiretroviral therapy (ART) is the only possible way to extend the life of people living with HIV (PLHIV), improve its quality and reduce the transmission of the virus to others. ART should be aimed at suppressing HIV replication with minimal risk of early and late side effects and drug resistance, as well as minimal disruption to normal life. Suppression of HIV replication helps to restore the function of the immune system, ensure the normal physical and mental development of PLHIV, minimize the risk of opportunistic infections and cancer, and reduce AIDS and mortality rates.

Endoscopy of the nasal cavity is the most reliable method for examining the nasal cavity, the state of the paranasal sinuses and their natural fistulas and plays a leading role in the diagnosis, an objective assessment of the effectiveness of the treatment and the choice of the optimal surgical intervention. In this article, the authors present the results of endoscopic examination of the nasal cavity in patients with chronic inflammatory diseases of the nose and paranasal sinuses. Endoscopic examination revealed mainly edema of the nasal mucosa, hypertrophy of the turbinates (lower), hyperemia, mucous secretions of the nasal passages and polyposis changes.

It is now known that any of the known pathogens can cause myocardial damage, including myocarditis. Often, viruses that can directly interact with cardiomyocytes become an etiological factor, which leads to cell apoptosis. The authors present the results of a biochemical study of blood in patients with diseases of the nose and paranasal sinuses against the background of myocarditis. It is indicated that the disease of the nose and paranasal sinuses affect the biochemical parameters of the blood and, in turn, exacerbate the course of myocarditis.