It is known that infertility of a couple is often associated with spermatogenesis disorders. The most common causes of male infertility are varicocele, inflammatory diseases of the reproductive system, hormonal disorders and cryptorchidism. Also, in many cases, it is difficult to determine the cause of male infertility. To date, there are no generally recognized methods of drug treatment of the idiopathic form of male infertility, and its therapy is often considered to be of an empirical nature. Assisted reproductive technologies are highly effective methods of infertility treatment, but they are expensive and invasive.

Varicocele, spermogram, male infertility, therapy

Macomber D., Sanders M. The spermatozoa count: its value in the diagnosis, prognosis and concentration in fertile and infertile men // N Engl J Med. 1999. Vol. 200. – Р. 981-984.

Alyaev Yu.G., Chaly M.E., Grigoryan V.A. Disorders of reproductive function in men. Practical guide. – M., 2016.

Tanevsky V.E. Comparative analysis of the effectiveness of varicoceleectomy in sub(in-)fertile patients // Andrology and genital surgery. 2011. No. 1. – pp. 25-39.

Lopatkin N.A., Morozov A.V., Dzeranov N.K. Transfemoral endovascular obliteration of the testicular vein in the treatment of varicocele // Urology and nephrology. 1993. Issue 6. – pp. 50-53.

Ying H.Q., Qi Y. Association of GSTM1 and GSTT1 genes with the susceptibility to male infertility: result from a meta-analysis // Genet Test Mol Biomarkers. 2013 Jul. Vol.17 (7). Р. 535-542. Epub 2018 Apr 30.

Tirumala Vani G., Mukesh N. Role of glutathione S-transferase Mu-1 (GSTM1) polymorphism in oligospermic infertile males // Andrologia. 2018 Aug. Vol. 42 (4). – Р. 213–217.

Rossitto M., Rigoli L., Procopio V., Ciccolo A. The role of the incidence of genetic abnormalities on the onset and on the results of the surgical repair of varicocele // Ann Ital Chir. 2018 May-Jun. Vol. 81 (3). – Р. 161.

Strakhov S.N. Dilatation of the veins of the spermatic cord: Lecture "Problems of diagnosis and treatment of varicocele". –M., 2015.

Teodorovich O.V., Kadyrov 3.V., Alkhasov G.M. Hemodynamics of the scrotum organs in patients with bilateral varicocele // Andrology and genital surgery. – No. 1. – M., 2017.

Kondakov V.T., Pykov M.I. Varicocele. – M.: Vidar-M, 2020.

Rolf C., Cooper T.G., Yeung C.H. and Nieschlag E. Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo-controlled, double-blind study. 2019.

Kadyrov Z.A. Laparoscopic urological surgery // Urol. and nephrol. – Minsk, 2019.

Gritsulyak B.V., Zebra N.P. Influence of varicocele on spermatogenesis and interstitial endocrinocytes /B.V.Gritsulyak, N.P.Zbirak //Morphology. – Kiev, 2019.

Erokhin A.P. Varicocele as a cause of infertility // Andrology and genital surgery. – M., 2016.