The aim of the study was to study the role of brain sodium uretic peptide in the diagnosis of chronic heart failure in patients with type 2 diabetes mellitus. For the period 2019-2021, we identified and selected 185 patients as an object of research based on the materials of their appeal to medical institutions in Andijan aged 30 and older.  The patients underwent general clinical, biochemical, hormonal, genetic blood tests, as well as ECG, Echo-ECG and other instrumental studies. The mean values of NT proBNP significantly differed in all groups and, at the same time, they were significantly higher in the group of patients with diabetes mellitus + CHF compared to those in patients with isolated CHF. We selected median NT-proBNP levels in increasing NT-proBNP tertiles in the range from 125 to 250 pg / ml, from 250 to 500 pg / ml, and above 500 pg / ml.  The dynamics of their concentration, mainly NT-proBNP, can help in assessing the effectiveness of the therapy and the need for dose titration of drugs.

Type 2 Diabetes Mellitus, Chronic Heart Failure, Hormones

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